As federal and state funding for health programs shrinks, the Knight Cancer Institute at Oregon Health & Science University just hit the jackpot: A $2 billion donation from Nike cofounder Phil Knight, who once attended the school, and his wife, Penny. It’s the largest single gift to a university in U.S. history. “This gift,” said OHSU president Shereef Elnahal, MD, MBA, “is an unprecedented investment in the millions of lives burdened with cancer.”